Dr. Small is Professor of Medicine at UCSF (University of California, San Francisco). He holds a number of leadership roles, serving as Leader of the UCSF Prostate Cancer Program, and as Deputy Director of the UCSF Helen Diller Family Comprehensive Cancer Center. He has served as Chief of the Division of Hematology and Oncology for 10 years, and most recently he has assumed the position of Chief Scientific Officer in the UCSF Helen Diller Family Comprehensive Cancer Center. Nationally, he serves on the ASCO Board of Directors, and chairs a number of External Advisory Boards for other Cancer Centers.
Dr. Small’s research interests lie in clinical and translational research in advanced prostate cancer, including trial design, and development of novel agents. He piloted the early trials targeting the androgen receptor in advanced prostate cancer, developing ketoconazole and contributing to an understanding of its mechanisms of activity and resistance. Subsequently Eric was centrally involved with the development of two novel androgen signaling inhibitors, abiraterone acetate and apalutamide, from first in human studies to FDA approval.
Dr. Small has also been involved in the early application of immunotherapy to prostate cancer, developing sipuleucel T from first in human studies through FDA approval, and undertaking the first in human testing of ipilimumab, the first immune check point inhibitor to be clinically developed.
Dr. Dornan is Senior Vice President and Head of Research at Bolt Biotherapeutics. Prior to Bolt, Dr. Dornan was Head of Oncology Research at Gilead and was dedicated to identifying and developing anti-cancer therapeutics for PD-1-refractory patients and cancer driver targeted therapies. Before that, he spent 10 years at Genentech serving in roles of increasing responsibility and played key roles in target discovery and validation. Dr. Dornan received his Ph.D. from the University of Dundee, UK.
Dr. Blackburn is Chief Development Officer and Founder at Amygdala Neurosciences. Previously he was Founder and CEO at Rapidscan Pharma Solutions and SVP R&D at CV Therapeutics. Dr. Blackburn successfully oversaw the development and commercialization of Lexiscan and Ranexa and helped place seven products into clinical development for multiple indications. He was in charge of every facet of the development of drugs at CV Therapeutics, including launching Lexiscan and Ranexa. He received his Ph.D from the University of Texas at Austin.
Dr. Diamond is Professor of Cellular and Molecular Pharmacology at University of California, San Francisco, and Founding Director at Ernest Gallo Clinic and Research Center. Dr. Diamond is a world-renowned GPCR expert and experienced in drug development for adenosine receptor inhibitors for Parkinson’s disease, addiction and prostate cancer. Dr. Diamond was Senior Advisor at Gilead Sciences. He received an M.D. and Ph.D. from Harvard University.